Abstract
Although historically considered as a typical nosocomial pathogen, meticillin-resistant Staphylococcus aureus (MRSA) has rapidly emerged as a cause of infections in the community. In Europe, the prevalence of infections due to community-acquired (CA)-MRSA is lower than in the United States, although recent reports highlight that these infections are on the rise (Wallin et al., 2008). Most commonly, CA-MRSA causes skin and soft-tissue infections, while severe and life-threatening infections, such as necrotizing pneumonia, necrotizing fasciitis and severe sepsis, represent rare cases (Wang et al., 2005). We report a case of CA-MRSA bacteraemia with cavernous sinus thrombosis, meningitis and brain abscess in a previously healthy American. We consecutively reviewed all cases of CA-MRSA with central nervous system (CNS) involvement available in the literature.