Research Article

Passive secretory immunity against Salmonella typhimurium demonstrated with foster mouse pups

Journal of Medical Microbiology 1991; 35(1):53

PubMed

Abstract

Mice immunised by drinking water containing an Aro- mutant strain of Salmonella typhimurium produced intestinal IgA antibodies after a memory response which was demonstrated by measuring copro-antibodies. After oral challenge with a virulent strain of S. typhimurium, foster mouse pups placed with immunised mothers survived longer than control pups held with non-immunised mothers.