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Research Article

Enhancement of the antituberculosis activity of weak acids by inhibitors of energy metabolism but not by anaerobiosis suggests that weak acids act differently from the front-line tuberculosis drug pyrazinamide

Gu, Peihua, Constantino, Luis, Zhang, Ying

Journal of Medical Microbiology 2008; 57(9):1129 · https://doi.org/10.1099/jmm.0.2008/000786-0

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Abstract

Abbreviations: ASP, aspirin; BA, benzoic acid; DBA, 4-dodecyloxylbenzoic acid; DCCD, N,N'-dicyclohexylcarbodiimide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PHB, propyl 4-hydroxybenzoate; POA, pyrazinoic acid; PZA, pyrazinamide; SA, salicylic acid; TB, tuberculosis.