Bacillus cereus Nhe is a pore-forming toxin with structural and functional properties similar to the ClyA (HlyE, SheA) family of haemolysins, able to induce osmotic lysis in epithelia

Multiple sequence alignment of ClyA from E. coli K-12 and the mature sequences of the Hbl and Nhe components from B. cereus ATCC 14579, created using clustal w. Hydrophobic regions are boxed and in bold type, identical residues are indicated in red type on a yellow background, while blocks of identical and similar residues are indicated by blue and green backgrounds, respectively.