Article

Kinetics of Bacterial Growth: Relationship between Population Density and Specific Growth Rate of Continuous Cultures

Journal of General Microbiology 1959; 21(1):40–50 · https://doi.org/10.1099/00221287-21-1-40

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Abstract

SUMMARY: Results from studies of continuous cultures of Aerobacter aerogenes growing in chemically denned media indicate that specific growth rate (R) is a function of population density (P) as well as the concentration of the limiting nutrient (S). From these observations, and those of others, the following model for bacterial growth is derived:

mic-21-1-40-si1.gif

where um and B are growth parameters that are constants under defined conditions. This model is believed to have general applicability and to account for bacterial growth in both batch and continuous cultures.