Research Article

The Influence of Emetine on the Induction of Interferon by Poly-I:Poly-C in Swiss Mice

Journal of General Virology 1975; 26(2):197 · https://doi.org/10.1099/0022-1317-26-2-197

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Abstract

The effect of emetine on the in vivo production of interferon by Swiss mice stimulated with poly-I:poly-C, was studied. 100 µg of emetine per mouse yielded a 16-fold increase in interferon production. Maximal production of interferon was achieved 2 h after the simultaneous injection of emetine and poly-I:poly-C.