Research Article

Absence of poly (A) from the infective RNA of Nodamura virus -- Newman and Brown 30 (1): 137 -- Journal of General Virology

Journal of General Virology 30(1):137

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Abstract

With the exception of phage Qbeta, the RNAs of all the other small icosahedral RNA viruses so far examined contain a poly (A) tract. This tract has been implicated in the infectivity of poliovirus RNA. We have now shown that Nodamura virus, a divided genome virus from which infective RNA can be extracted, does not contain any poly (A) tracts. This evidence with Nodamura virus shows that poly (A) is not a necessary requirement for the infectivity of virus RNA molecules.