Research Article

Evidence for Early Nuclear Antigens in Cytomegalovirus-Infected Cells

Journal of General Virology 1976; 32(2):315 · https://doi.org/10.1099/0022-1317-32-2-315

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Abstract

Human cytomegalovirus (CMV) induces nuclear antigens resembling the Epstein-Barr nuclear antigen (EBNA) as early as 3 h after infection. These early antigens can be detected only with the anti-complement immunofluorescence staining (ACIF) technique. Synthesis of these new antigens is not influenced by cytosine arabinoside (ara-C).