Research Article

Cytopathic Effect and Plaque Formation by Arboviruses in a Continuous Cell Line (XTC-2) from the Toad Xenopus laevis

Journal of General Virology 1977; 35(2):335 · https://doi.org/10.1099/0022-1317-35-2-335

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Abstract

Forty-six arboviruses were tested for c.p.e. and/or plaque formation in an amphibian cell line. C.p.e. was observed with a high proportion of the viruses tested. Comparative plaque assay, in the XTC-2 cells at 28 °C and Vero cells at 37 °C, suggests that these systems are comparable in sensitivity and susceptibility to infection. Practical uses of this cell line are discussed.