Abstract
The biochemistry of vaccinia virus replication in two permissive (BSC-40, L-929), and two non-permissive (CHO, MDBK) cell lines has been compared. While CHO and MDBK cells differentially allowed expression of the various stages in the vaccinia developmental programme, neither cell supported production of any infectious progeny virions.
* Present address: Biophysics Laboratory, University of Wisconsin-Madison, Madison, Wisconsin 53706, U.S.A.
† Present address: Department of Cellular Biology, Scripps Clinic and Research Foundation, La Jolla, California 92037, U.S.A.
‡ Present address: Department of Biochemistry, Schools of Medicine and Dentistry, State University of New York, Buffalo, New York 14214, U.S.A.