Typing Mycobacterium tuberculosis with Mycobacteriophage Bo4

Mycobacteriophage B04 grown on the indicator host strain Mycobacterium fortuitum SN203 was restricted and modified by Mycobacterium tuberculosis H₃₇R_v. Phage B04·H₃₇R_v was restricted and modified by the alternate host SN 203. M. tuberculosis strain Myc 1025 was described as a r^-m^- isolate. By using the mycobacterial prototype strains for phage typing wild M. tuberculosis isolates, it was demonstrated that only the modified phage B04·H₃₇R_v was a potential typing phage.