Research Article

Inactivation of Respiratory Syncytial Virus in Aerosol

Journal of General Virology 1969; 5(3):405 · https://doi.org/10.1099/0022-1317-5-3-405

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Abstract

Aerosols of respiratory syncytial virus were kept at different relative humidities (RH). Viability was studied by a plaque method. Virus recoveries 1 min. after aerosolization were highest at high RH. The stability of the aerosol was maximal at 60% RH. The total decay after 61 min. varied from 1.1 log. p.f.u. to 2.5 log. p.f.u., with peak values at 30% RH (2.3 log. p.f.u.) and 80% RH (2.5 log. p.f.u.), suggesting two processes with different kinetics. Oxidation was excluded as a cause of inactivation by experiments in pure nitrogen.

* Present address: National Institute of Public Health, Sterrenbos 1, Utrecht, The Netherlands.