Abstract
Nine proteins accumulate in nuclei of arginine-deprived herpes simplex virus-infected cells. Of these, eight were found to bind to double-stranded DNA-cellulose and to elute with 0·3 and 0·6 M-KCl, while one of 160000 mol. wt. had no affinity for the DNA. Five of the DNA-binding proteins were identified as virus enzymes: two were DNA polymerases, two were alkaline DNases and one was the thymidine kinase.