Research Article

Temperature-sensitive Mutants in Two Distinct Complementation Groups of Herpes Simplex Virus Type 1 Specify Thermolabile DNA Polymerase

Journal of General Virology 1981; 54(1):219 · https://doi.org/10.1099/0022-1317-54-1-219

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Abstract

We and others have previously shown that a mutant in herpes simplex virus type 1 (HSV-1) complementation group 14 induces a virus-specified DNA polymerase that is temperature-sensitive in vitro. Here we report that HSV-1 tsC7 in complementation group 13 also induces a thermolabile DNA polymerase.