Research Article

Inhibition of La Crosse Virus Replication by Monensin, a Monovalent Ionophore

Journal of General Virology 1982; 59(1):193 · https://doi.org/10.1099/0022-1317-59-1-193

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Abstract

The effect of monensin, a monovalent ionophore, on La Crosse virus particle formation and polypeptide synthesis was examined. Monensin inhibited the release of virus particles (both infectious and non-infectious) from infected BHK-21 cells. Monensin had no detectable effect on the synthesis of polypeptides G1, G2 and N.