Research Article

Infection of Chick Embryo Fibroblasts With Template Active RNA From Avian Myeloblastosis Virus

Journal of General Virology 1970; 6(1):163 · https://doi.org/10.1099/0022-1317-6-1-163

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Abstract

The effect of different doses of viral RNA extracted from avian myeloblastosis virus was tested on RIF-free chick embryo cells. The results showed that the number of cells with positive gs-antigen was probably related to the dose of RNA. The specificity of viral RNA action was shown by a fluorescent antibody method and by the use of ribonuclease.

* Present address: Houghton Poultry Research Station, Houghton, Huntingdon, England.

Part of the work reported in this paper was undertaken during the tenure of an Eleanor Roosevelt International Cancer Fellowship of the American Cancer Society awarded by the International Union Against Cancer.