Abstract
The present work reports on the sites of lactic-, isocitric-, succinic-, malic- and glucose-6-phosphatic dehydrogenases in chick embryo fibroblast cultures infected with Rous sarcoma virus (SCHMIDT-RUPPIN strain) using cytochemical methods.
It was found that in RSV transformed cells reactive sites are both more numerous and appear more heavily stained than uninfected, dividing fibroblasts or fibroblasts infected with two other viruses of the avian leukosis group (RAV 12).
These results seem to indicate that, in the case of Rous sarcoma virus infection of the chicken and under these experimental conditions, the glycolysis of the transformed (neoplastic) cells is not accompanied by a decrease of the respiratory enzymes studied here.