Research Article

A 28 000 Molecular Weight Human Cytomegalovirus Structural Polypeptide Studied by means of a Specific Monoclonal Antibody

Journal of General Virology 1985; 66(11):2507 · https://doi.org/10.1099/0022-1317-66-11-2507

View at publisher PubMed

Abstract

We have produced a monoclonal antibody against human cytomegalovirus (HCMV) which recognizes a structural protein of 28 000 mol. wt. which is present in both the cytoplasm of infected cells during the late phase of the viral replication cycle and in the extracellular viral particles. This antigen was detected in all HCMV strains assayed and reacted with human sera having anti-HCMV antibodies.