Research Article

Affinity-purified Varicella-Zoster Virus Glycoprotein gp1/gp3 Stimulates the Production of Neutralizing Antibody

Journal of General Virology 1985; 66(8):1795 · https://doi.org/10.1099/0022-1317-66-8-1795

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Abstract

Varicella-zoster virus glycoprotein gp1/gp3 was purified by affinity chromatography using anti-gp1/gp3 monoclonal antibody 19.1 linked to CNBr-activated Sepharose CL-4B. Rabbits immunized with purified glycoprotein gp1/gp3 developed monospecific neutralizing antibody.