Abstract
The enzyme responsible for cauliflower mosaic virus (CaMV) DNA replication has been studied by isolating virus replication complexes and assaying the associated polymerase activity using activated calf thymus DNA or poly(rCm).oligo(dG)1218 as template-primer. The activity of the enzyme was specifically inhibited by immune serum raised against a synthetic peptide corresponding to a portion of the viral gene V protein. This result provides further evidenes that this protein is the reverse transcriptase involved in CaMV replication.