Abstract
1 Instituto de Investigaciones Bioquímicas, Fundación Campomar-CONICET and Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Avenida Patricias Argentinas 435, 1405 Buenos Aires
and2 Centro de Virología Animal (CEVAN-CONICET), Serrano 661, 1414 Buenos Aires, Argentina
The structures of the rearranged genomic segment 11 of two spontaneous swine rotavirus strains were determined. We found that the rearrangements involved the duplication of normal segment 11 in a head-to-tail orientation, and partial deletions in both monomers. The open reading frame for VP11, the protein encoded by normal segment 11, was maintained. We also showed that the two rearranged genes were transcribed into RNA molecules of the same length as their corresponding genomic segments.