Neutralization activity in a geographically diverse East London cohort of human immunodeficiency virus type 1-infected patients: clade C infection results in a stronger and broader humoral immune response than clade B infection

Dreja, Hanna, O'Sullivan, Eithne, Pade, Corinna, Greene, Kelli M., Gao, Hongmei, Aubin, Keith, Hand, James, Isaksen, Are, D'Souza, Carl, Leber, Werner, Montefiori, David, Seaman, Michael S., Anderson, Jane, Orkin, Chloe, McKnight, Aine

Abstract

¹ HIV/AIDS Group, Centre for Immunology and Infectious Disease, The Blizard Institute of Cell and Molecular Science, Barts and The London, Queen Mary's School of Medicine and Dentistry, 4 Newark Street, London E1 2AT, UK
² Laboratory for AIDS Vaccine Research & Development, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
³ HIV Clinical Research, Grahame Hayton Unit, Barts and The London Hospital, Whitechapel Road, London E1 1BB, UK
⁴ Centre for the Study of Sexual Health and HIV, Homerton University Hospital NHS Foundation Trust, London E9 6SR, UK
⁵ Department of Medicine, Division of Viral Pathogenesis, Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, MA 02215, USA