Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency

¹ Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA
² School of Dentistry, University of California, Los Angeles, CA 90095, USA
³ Department of Biological Chemistry, University of California, Los Angeles, CA 90095, USA
⁴ Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA
⁵ Center for Infection and Immunity, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China
⁶ Human Oncology and Pathogenesis Program and Department of Neurology, Memorial Sloan–Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
⁷ Department of Human Genetics, University of California, Los Angeles, CA 90095, USA