Research Article

Complete genome analysis of hepatitis C virus subtypes 6t and 6u

Journal of General Virology 2008; 89(5):1276 · https://doi.org/10.1099/vir.0.83593-0

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Abstract

Hepatitis C virus (HCV) genomes exhibit high nucleotide sequence diversity. In this study, we performed complete genome sequence analysis of 11 HCV genotype 6 samples from Vietnam and Thailand. We identified nine HCV complete genomes belonging to subtypes 6a (D9), 6e (D42 and D88), 6f (TH52), 6i (TH24), 6l (D33), 6n (TH22 and TH31) and 6o (D85). Phylogenetic analysis of the core/E1 and NS5B regions from unclassified genotype 6 isolates from Asian immigrants in Canada revealed that two other viruses (D49 and D83) could be classified as novel candidates of HCV subtypes 6t and 6u.

The GenBank/EMBL/DDBJ sequence accession numbers for the sequences reported in this study are EU246930–EU246940.

Supplementary material is available with the online version of this paper.